This paper presents the design and evaluation of the hardware circuit for electronic stethoscopes with heart sound cancellation\ncapabilities using field programmable gate arrays (FPGAs). The adaptive line enhancer (ALE) was adopted as the filtering\nmethodology to reduce heart sound attributes from the breath sounds obtained via the electronic stethoscope pickup. FPGAs\nwere utilized to implement the ALE functions in hardware to achieve near real-time breath sound processing.We believe that such\nan implementation is unprecedented and crucial toward a truly useful, standalone medical device in outpatient clinic settings. The\nimplementation evaluation with one Altera cyclone IIââ?¬â??EP2C70F89 shows that the proposed ALE used 45% resources of the chip.\nExperiments with the proposed prototype were made using DE2-70 emulation board with recorded body signals obtained from\nonline medical archives. Clear suppressions were observed in our experiments from both the frequency domain and time domain\nperspectives.
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